Endocrine Abstracts

We present a complex case of basal skull prolactinoma presenting with CSF rhinorrhoea and without elevated prolactin. Our case is a 41 year woman who presented 2 years ago with streptococcal meningitis and CSF rhinorrhoea. Initial imaging suggested right sphenoid tumour eroding the skull base involving structures in anterior and middle cranial fossa. After the tumour was biopsied by ENT team, she developed signs of recurrent meningitis, therefore referred to neurosurgery. She ...

A 56-year-old gentleman diagnosed with galactosemia by open liver biopsy at the age of one was referred by GP with longstanding complaints of increasing lethargy, low mood and chronic anaemia. Initial investigations revealed normocytic anemia with a normal renal function, ESR, haematinics, calcium and myeloma screen. Endocrine tests revealed anterior hypopituitarism (TSH: 4.4, FreeT4: 4.5, LH: 0.5, FSH: 2, testosterone: <0.1, prolactin: 27, IgF-1: <3.3, random cortisol...

We report potential effects of antituberculosis (TB) treatment on vitamin D metabolism in the immediate postoperative period following total thyroidectomy.A 50-year woman of Chinese origin was incidentally found to have papillary thyroid carcinoma with local nodal metastasis following FDG–PET imaging done to assess nature of lung nodules on chest X-ray and CT chest. The nature of lung lesion was uncertain and commenced on empirical TB treatment (fou...

We report a case surviving hyperparathyroid crisis, with the second highest serum calcium concentration ever reported.A 45-year-old female with type 2 diabetes and mixed hyperlipidaemia was admitted with extreme lethargy, dehydration and drowsiness. Serum corrected calcium was 6.49 mmol/l (2.2–2.6 mmol/l), phosphate 1.79 mmol/l, intact parathyroid hormone (PTH) 1059 pg/ml (15–65 pg/ml), creatinine 124 μmol/l and urea 16.0 mmol/l.<p cla...